MEERMAN, JOHN H. N.: search on Z-Library

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1

Prediction of Ligand Binding Affinity and Orientation of Xenoestrogens to the Estrogen Receptor by Molecular Dynamics Simulations and the Linear Interaction Energy Method

van Lipzig, Marola M. H., ter Laak, Antonius M., Jongejan, Aldo, Vermeulen, Nico P. E., Wamelink, Mirjam, Geerke, Daan, Meerman, John. H. N.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 145 KB

english, 2004

2

Simultaneous determination of eight lipid peroxidation degradation products in urine of rats treated with carbon tetrachloride using gas chromatography with electron-capture detection

Loeckie L De Zwart, Jennifer Venhorst, Marjolein Groot, Jan N.M Commandeur, Ralph C.A Hermanns, John H.M Meerman, Ben L.M Van Baar, Nico P.E Vermeulen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1997

Language:

english

File:

PDF, 986 KB

english, 1997

3

Ultra High Content Image Analysis and Phenotype Profiling of 3D Cultured Micro-Tissues

Di, Zi, Klop, Maarten J. D., Rogkoti, Vasiliki-Maria, Le Dévédec, Sylvia E., van de Water, Bob, Verbeek, Fons J., Price, Leo S., Meerman, John H. N., Oshima, Robert

Journal:

Year:

2014

Language:

english

File:

PDF, 1.80 MB

english, 2014

4

Deuterium Isotope Effect on the Metabolism of the Flame Retardant Tris(2,3-dibromopropyl) Phosphate in the Isolated Perfused Rat Liver

BEERENDONK, GEERTJE J. M. VAN, PEARSON, PAUL G., MEIJER, DIRK K. F., MULDER, GERARD J., NELSON, SIDNEY D., MEERMAN, JOHN H. N.

Journal:

Toxicological Sciences

Year:

1995

Language:

english

File:

PDF, 5.69 MB

english, 1995

5

Loss of Nuclear p53 Protein in Preneoplastic Rat Hepatocytes Is Accompanied by Mdm2 and Bcl-2 Overexpression and by Defective Response to DNA Damage In Vivo

Hilde E Van Gijssel, Lena C Ohlson, Ulla-Britta Torndal, Gerard J Mulder, Lennart C Eriksson, Inger Porsch-Hällström, John H Meerman

Journal:

Year:

2000

Language:

english

File:

PDF, 725 KB

english, 2000

6

675 Formation of estrogenic metabolites from polycyclic aromatic hydrocarbons and halogenated biphenyls by cytochrome P450 activity and development of a predictive computational model for binding to the estrogen receptor

John H.N. Meerman, Marola M.H. van Lipzig, A.M. ter Laak, Mirjam Wamelink, Daan Geerke, Nico P.E. Vermeulen, Aldo Jongejan

Journal:

Toxicology Letters

Year:

2003

Language:

english

File:

PDF, 54 KB

english, 2003

7

Epidermal growth factor receptor signalling in human breast cancer cells operates parallel to estrogen receptor α signalling and results in tamoxifen insensitive proliferation

Moerkens, Marja, Zhang, Yinghui, Wester, Lynn, van de Water, Bob, Meerman, John HN

Journal:

Year:

2014

Language:

english

File:

PDF, 1009 KB

english, 2014

8

Sulfation and Glucuronidation as Competing Pathways in the Metabolism of Hydroxamic Acids: The Role of N,O-Sulfonation in Chemical Carcinogenesis of Aromatic Amines

Gerard J. Mulder and John H. N. Meerman

Journal:

Environmental Health Perspectives

Year:

1983

Language:

english

File:

PDF, 1.25 MB

english, 1983

9

Metabolic Profiling of Endocrine-Disrupting Compounds by On-Line Cytochrome P450 Bioreaction Coupled to On-Line Receptor Affinity Screening

Van Liempd, Sebastiaan M., Kool, Jeroen, Meerman, John H., Irth, Hubertus, Vermeulen, Nico P.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 204 KB

english, 2007

10

Temporal and functional dynamics of the transcriptome during nerve growth factor-induced differentiation

Thomas F. Dijkmans, Lenneke W. A. van Hooijdonk, Theo G. Schouten, Jessica T. Kamphorst, Anette C. A. Vellinga, John H. N. Meerman, Carlos P. Fitzsimons, E. Ron de Kloet, Erno Vreugdenhil

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 478 KB

english, 2008

11

Correlation between clastogenicity and promotion activity in liver carcinogenesis by N-hydroxy-2-acetylaminofluorene, N-hydroxy-4'-fluoro-4-acetylaminobiphenyl and N-hydroxy-4-acetylaminobiphenyl

van de Poll, Monique L.M., van der Hulst, Dolinda A.M., Tates, Ad D., Meerman, John H.N.

Journal:

Year:

1990

Language:

english

File:

PDF, 2.31 MB

english, 1990

12

Differential activation of promutagens by alloenzymes of human sulfotransferase 1A2 expressed in Salmonella typhimurium

Meinl, Walter, Meerman, John HN, Glatt, Hansruedi

Journal:

Pharmacogenetics

Year:

2002

Language:

english

File:

PDF, 208 KB

english, 2002

13

Development and validation of a microsomal online cytochrome P450 bioreactor coupled to solid-phase extraction and reversed-phase liquid chromatography

Sebastiaan M. van Liempd, Jeroen Kool, Jelle Reinen, Tim Schenk, John H.N. Meerman, Hubertus Irth, Nico P.E. Vermeulen

Journal:

Journal of Chromatography A

Year:

2005

Language:

english

File:

PDF, 225 KB

english, 2005

14

Simultaneous determination of tyrosine, phenylalanine and deoxyguanosine oxidation products by liquid chromatography–tandem mass spectrometry as non-invasive biomarkers for oxidative damage

Hilmi Orhan, Nico P.E Vermeulen, Cornelis Tump, Herman Zappey, John H.N Meerman

Journal:

Journal of Chromatography B

Year:

2004

Language:

english

File:

PDF, 153 KB

english, 2004

15

Electrochemical Detection and Quantification of the Acetylated and Deacetylated C8-Deoxyguanosine DNA Adducts Induced by 2-Acetylaminofluorene

Sandra A.M. Bol, Anton J.L. de Groot, Roeline B. Tijdens, John H.N. Meerman, Leon H.F. Mullenders, Albert A. van Zeeland

Journal:

Analytical Biochemistry

Year:

1997

Language:

english

File:

PDF, 137 KB

english, 1997

16

Bioactivation of the hepatocarcinogen N-hydroxy-2-acetylaminofluorene by sulfation in the rat liver changes during the cell cycle

Ron A.H.J. Gilissen, John H.N. Meerman

Journal:

Year:

1992

Language:

english

File:

PDF, 386 KB

english, 1992

17

A physiologically relevant HepG2 cell based 3D cell culture model for high throughput toxicity studies

Price, Leo, van de Water, Bob, van Delft, Joost, Commandeur, Jan, Braver, Michiel, Coonen, Maarten, Ramaiahgari, Sreenivasa, Jennen, Danyel, Meerman, John

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 72 KB

english, 2013

18

Formation of six cyclic 1,N2-hydroxybromopropanodeoxyguanosine isomers upon reaction of 2-bromoacrolein with 2'-deoxyguanosine

Meerman, John H. N., Pearson, Paul G., Meier, G. Patrick, Nelson, Sidney D.

Journal:

Journal of Organic Chemistry

Year:

1988

Language:

english

File:

PDF, 1.41 MB

english, 1988

19

Formation of thymidine adducts and cross-linking potential of 2-bromoacrolein, a reactive metabolite of tris(2,3-dibromopropyl)phosphate

van Beerendonk, Geertje J.M., Nivard, Madeleine J.M., Vogel, Ekkehart W., Nelson, Sidney D., Meerman, John H.N.

Journal:

Year:

1992

Language:

english

File:

PDF, 550 KB

english, 1992

20

Immobilization of solubilized UDP-glucuronosyltransferase from rat liver microsomes to Sepharose 4B

Ron A.H.J. Gilissen, John H.N. Meerman, Gerard J. Mulder

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 339 KB

english, 1992

21

Some nonylphenol isomers show antiestrogenic potency in the MVLN cell assay

Thomas G. Preuss, Hande Gurer-Orhan, John Meerman, Hans Toni Ratte

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 451 KB

english, 2010

22

The role of N -sulfation in the N hydroxy-2-acetylaminofluorene-mediated outgrowth of diethylnitrosamine-initiated hepatocytes to γ-glutamyltranspeptidase-positive foci in male rat liver

Kroese, E. Dinant, van de Poll, Monique L.M., Mulder, Gerard J., Meerman, John H. N.

Journal:

Year:

1988

Language:

english

File:

PDF, 597 KB

english, 1988

23

Automated Analysis of NF-κB Nuclear Translocation Kinetics in High-Throughput Screening

Di, Zi, Herpers, Bram, Fredriksson, Lisa, Yan, Kuan, van de Water, Bob, Verbeek, Fons J., Meerman, John H. N., Androulakis, Ioannis P.

Journal:

Year:

2012

Language:

english

File:

PDF, 2.77 MB

english, 2012

24

Quantification of urinary o,o′-dityrosine, a biomarker for oxidative damage to proteins, by high performance liquid chromatography with triple quadrupole tandem mass spectrometry: A comparison with ion-trap tandem mass spectrometry

Hilmi Orhan, Stefan Coolen, John H.N. Meerman

Journal:

Journal of Chromatography B

Year:

2005

Language:

english

File:

PDF, 202 KB

english, 2005

25

Biomarkers of free radical damage: Applications in experimental animals and in humans

Loeckie L de Zwart, John H.N Meerman, Jan N.M Commandeur, Nico P.E Vermeulen

Journal:

Free Radical Biology and Medicine

Year:

1999

Language:

english

File:

PDF, 276 KB

english, 1999

26

Genotoxicity of the flame retardant tris(2,3-dibromopropyl)phosphate in the rat and Drosophila: effects of deuterium substitution

Van Beerendonk, Geertie J.M., Nivard, Madeleine J.M., Vogel, Ekkehart W., Nelson, Sidney D., Meerman, John H.N.

Journal:

Year:

1994

Language:

english

File:

PDF, 602 KB

english, 1994

27

Sulfation-dependent formation of N -acetylated and deacetylated DNA adducts of N -hydroxy-4-acetylamlnobiphenyl in male rat liver in vivo and in isolated hepatocytes

van de Poll, Monique L.M., Venizelos, Vicki, Meerman, John H.N.

Journal:

Year:

1990

Language:

english

File:

PDF, 722 KB

english, 1990

28

Evaluation of a novel high-throughput assay for cytochrome P450 2D6 using 7-methoxy-4-(aminomethyl)-coumarin

Jennifer Venhorst, Rob C.A Onderwater, John H.N Meerman, Nico P.E Vermeulen, Jan N.M Commandeur

Journal:

European Journal of Pharmaceutical Sciences

Year:

2000

Language:

english

File:

PDF, 134 KB

english, 2000

29

Simulations of the Estrogen Receptor Ligand-Binding Domain: Affinity of Natural Ligands and Xenoestrogens

Oostenbrink, B. Chris, Pitera, Jed W., van Lipzig, Marola M. H., Meerman, John H. N., van Gunsteren, Wilfred F.

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 205 KB

english, 2000

30

Comparative toxicity of (+)-(R)- and (−)-(S)-1,2-dibromo-3-chloropropane

Samir A. Kouzi, Erik J. Søderlund, Erik Dybing, John H. N. Meerman, Sidney D. Nelson

Journal:

Year:

1995

Language:

english

File:

PDF, 551 KB

english, 1995

31

Urinary excretion of biomarkers for radical-induced damage in rats treated with NDMA or diquat and the effects of calcium carbimide co-administration

Loeckie L de Zwart, Nico P.E Vermeulen, Ralph C.A Hermanns, Jan N.M Commandeur, Paul J.M Salemink, John H.N Meerman

Journal:

Chemico-Biological Interactions

Year:

1999

Language:

english

File:

PDF, 345 KB

english, 1999

32

Lack of mammalian mutagenicity of the potent bacterial mutagen tris(2,3-dibromopropyl)phosphate and its metabolite 2-bromoacrolein

Geertje J.M van Beerendonk, Johanna C Klein, Roeline B Tijdens, Elgin G.R Lichtenauer-Kaligis, Judith G Tasseron-de Jong, John H.N Meerman

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

1998

Language:

english

File:

PDF, 151 KB

english, 1998

33

Prevention of the hepatotoxic action of N-hydroxy-2-acetylaminofluorene in the rat by inhibition of NO-sulfation by pentachlorophenol

John H.N. Meerman, Gerard J. Mulder

Journal:

Year:

1981

Language:

english

File:

PDF, 447 KB

english, 1981

34

From Prices to Incomes: Agricultural Subsidization without Protection?

John Baffes and Jacob Meerman

Journal:

The World Bank Research Observer

Year:

1998

Language:

english

File:

PDF, 2.50 MB

english, 1998

35

P VII.2 - P VII.2 Expression of p53 by hepatocarcinogens and non- hepatocarcinogens and its role in tumour promotion

Hilde van Gijssel, Ulla Stenius, Leon Mullenders, John Meerman

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 130 KB

english, 1997

36

Sex differences in sulfation and glucuronidation of phenol, 4-nitrophenol and N-hydroxy-2-acetylaminofluorene in the rat in vivo

John H.N. Meerman, Chris Nijland, Gerard J. Mulder

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 417 KB

english, 1987

37

A novel microplate reader-based high-throughput assay for estrogen receptor binding

Gurer-Orhan, Hande, Kool, Jeroen, Vermeulen, Nico P. E., Meerman, John H. N.

Journal:

International Journal of Environmental & Analytical Chemistry

Year:

2005

Language:

english

File:

PDF, 364 KB

english, 2005

38

Screening the Oxidative Potential of Several Mono- and Di-Halogenated Biphenyls and Biphenyl Ethers in Rat Hepatocytes

Gurer-Orhan, Hande, Orhan, Hilme, Vermeulen, Nico, Meerman, John

Journal:

Combinatorial Chemistry & High Throughput Screening

Year:

2006

Language:

english

File:

PDF, 303 KB

english, 2006

39

DNA adduct formation in liver following the administration of [ 3 H]2-nitrofluorene to rats in vivo

Wierckx, Frank C.J., Wedzinga, Rinny, Timmers-Reker, Anja J.M., Beland, Frederick A., Meerman, John H.N., Mulder, Gerard J.

Journal:

Year:

1991

Language:

english

File:

PDF, 3.28 MB

english, 1991

40

Sulphation of N-hydroxy-4-aminobiphenyl and N-hydroxy-4-acetylaminobiphenyl by human foetal and neonatal sulphotransferase

Ron A.H.J. Gilissen, Robert Hume, John H.N. Meerman, Michael W.H. Coughtrie

Journal:

Biochemical Pharmacology

Year:

1994

Language:

english

File:

PDF, 616 KB

english, 1994

41

Selective inhibition of sulfate conjugation in the rat: Pharmacokinetics and characterization of the inhibitory effect of 2,6-dichloro-4-nitrophenol

Henk Koster, Ina Halsema, Egbert Scholtens, John H.N. Meerman, K. Sandy Pang, Gerard J. Mulder

Journal:

Biochemical Pharmacology

Year:

1982

Language:

english

File:

PDF, 665 KB

english, 1982

42

Sulfation of hydroxylamines and hydroxamic acids in liver cytosol from male and female rats and purified aryl sulfotransferase IV

Gilissen, Ron A.H.J., Ringer, David P., Stavenuiter, Hans J.F.C., Mulder, Gerard J., Meerman, John H.N.

Journal:

Year:

1992

Language:

english

File:

PDF, 520 KB

english, 1992

43

An unusual dearomatized adduct formed by reaction of 4'-fluoro-4-(acetylamino)biphenyl N-sulfate with deoxyadenosine

Van de Poll, Monique L. M., Venizelos, Vicky, Niessen, Wilfried M. A., Meerman, John H. N.

Journal:

Chemical Research in Toxicology

Year:

1991

Language:

english

File:

PDF, 780 KB

english, 1991

44

The role of specific DNA adducts in the induction of micronuclei by N-hydroxy-2-acetylaminofluorene in rat liver in vivo

van de Poll, Monique L.M., van der Hulst, Dolinda A.M., Tates, Ad D., Mulder, Gerard J., Meerman, John H.N.

Journal:

Year:

1989

Language:

english

File:

PDF, 648 KB

english, 1989

45

High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability

Hiemstra, Steven, Ramaiahgari, Sreenivasa C., Wink, Steven, Callegaro, Giulia, Coonen, Maarten, Meerman, John, Jennen, Danyel, van den Nieuwendijk, Karen, Dankers, Anita, Snoeys, Jan, de Bont, Hans, P

Journal:

Archives of Toxicology

Year:

2019

File:

PDF, 8.98 MB

2019

46

Lipid peroxidation and protein thiol depletion are not involved in the cytotoxicity of N-hydroxy-2-acetylaminofluorene in isolated rat hepatocytes

E.Dinant Kroese, Gerard Bannenberg, Peter Dogterom, Arthur B.J. Noach, J.Fred Nagelkerke, John H.N. Meerman

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 977 KB

english, 1990

47

Blockage of transcription as a trigger for p53 accumulation by 2-acetylaminofluorene DNA-adducts

Hilde E van Gijssel, Leon H.F Mullenders, Michiel F van Oosterwijk, John H.N Meerman

Journal:

Year:

2003

Language:

english

File:

PDF, 186 KB

english, 2003

48

Photoactivation of 2-nitrofluorene in vitro and in the rat in vivo . UVA-induced formation of reactive intermediates that bind covalently to RNA and protein

Wierckx, Frank C.J., van Henegouwen, Gerard M.J.Begijersbergen, Van den Broeke, Leon T., de Vries, Henk, Meerman, John H.N., Mulder, Gerard J.

Journal:

Year:

1992

Language:

english

File:

PDF, 438 KB

english, 1992

49

Simulations of the Estrogen Receptor Ligand-Binding Domain: Affinity of Natural Ligands and Xenoestrogens.

Oostenbrink, B. Chris, Pitera, Jed W., van Lipzig, Marola M. H., Meerman, John H. N., van Gunsteren, Wilfred F.

Journal:

Journal of Medicinal Chemistry

Year:

2001

File:

PDF, 13 KB

2001

50

High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability

Hiemstra, Steven, Ramaiahgari, Sreenivasa C., Wink, Steven, Callegaro, Giulia, Coonen, Maarten, Meerman, John, Jennen, Danyel, van den Nieuwendijk, Karen, Dankers, Anita, Snoeys, Jan, de Bont, Hans, P

Journal:

Archives of Toxicology

Year:

2019

Language:

english

File:

PDF, 8.98 MB

english, 2019

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